Question 1. Who among the following first saw and described a live cell?
- a) Robert Hooke.
- b) Anton Von Leeuwenhoek.
- c) Matthias Schleiden.
- d) Theodore Schwann.
Answer: b.
Question 2. Which scientist concluded, based on his studies on plant tissues, that the presence of a cell wall is a unique character of the plant cells?
- a) Matthias Schleiden.
- b) Theodore Schwann.
- c) Rudolf Virchow.
- d) Robert Brown.
Answer: b.
Question 3. The concept of "Omnis cellula-e cellula" regarding cell division was first proposed by?
- a) Rudolf Virchow.
- b) Theodore Schwann.
- c) Camillo Golgi.
- d) George Palade.
Answer: a.
Question 4. Which of the following is not true about a prokaryotic cell?
- a) They are generally smaller and multiply more rapidly than eukaryotic cells.
- b) They lack a well-defined nucleus.
- c) Genomic DNA is enveloped by a nuclear membrane.
- d) They possess plasmids in addition to genomic DNA.
Answer: c.
Question 5. The basic shape of a Bacillus bacterium is?
- a) Spherical.
- b) Comma-shaped.
- c) Rod-like.
- d) Spiral.
Answer: c.
Question 6. What is the typical size of a PPLO (Pleuropneumonia Like Organisms)?
- a) 0.02 µm.
- b) 0.1 µm.
- c) 1.0 to 2.0 µm.
- d) 10 to 20 µm.
Answer: b.
Question 7. The specialised differentiated form of cell membrane found in prokaryotes that helps in respiration and secretion is called?
- a) Chromatophore.
- b) Mesosome.
- c) Plasmid.
- d) Nucleoid.
Answer: b.
Question 8. In a bacterial cell envelope, the outermost layer is known as?
- a) Cell wall.
- b) Plasma membrane.
- c) Glycocalyx.
- d) Peptidoglycan layer.
Answer: c.
Question 9. If the glycocalyx of a bacterium is a thick and tough layer, it is specifically called?
- a) Slime layer.
- b) Capsule.
- c) Mesosome.
- d) Inclusion body.
Answer: b.
Question 10. Bacterial flagella are composed of three parts. Which of the following is the longest portion?
- a) Hook.
- b) Basal body.
- c) Filament.
- d) Pilus.
Answer: c.
Question 11. Which surface structures of bacteria play a role in mating or conjugation but not in motility?
- a) Flagella and Fimbriae.
- b) Pili and Fimbriae.
- c) Cilia and Flagella.
- d) Mesosomes and Chromatophores.
Answer: b.
Question 12. Prokaryotic ribosomes are of 70S type. What are their two subunits?
- a) 50S and 30S.
- b) 60S and 40S.
- c) 40S and 30S.
- d) 50S and 20S.
Answer: a.
Question 13. Several ribosomes may attach to a single mRNA to form a chain called?
- a) Dictyosome.
- b) Polysome.
- c) Centrosome.
- d) Nucleosome.
Answer: b.
Question 14. Gas vacuoles, which are a type of inclusion body, are found in?
- a) Blue-green, purple, and green photosynthetic bacteria.
- b) All heterotrophic bacteria.
- c) Mycoplasma.
- d) Fungi and Protists.
Answer: a.
Question 15. The detailed structure of the cell membrane was studied only after the advent of the electron microscope in the year?
- a) 1930s.
- b) 1950s.
- c) 1970s.
- d) 1990s.
Answer: b.
Question 16. In the human erythrocyte, the cell membrane consists of approximately?
- a) 40 percent protein and 52 percent lipid.
- b) 52 percent protein and 40 percent lipid.
- c) 60 percent protein and 30 percent lipid.
- d) 30 percent protein and 60 percent lipid.
Answer: b.
Question 17. According to the fluid mosaic model, the quasi-fluid nature of lipids enables lateral movement of proteins within the overall bilayer. This ability to move is measured as its?
- a) Elasticity.
- b) Permeability.
- c) Fluidity.
- d) Rigidity.
Answer: c.
Question 18. Neutral solutes typically move across the cell membrane by the process of?
- a) Active transport.
- b) Simple diffusion.
- c) Facilitated diffusion.
- d) Exocytosis.
Answer: b.
Question 19. The sodium-potassium pump is an example of?
- a) Passive transport.
- b) Osmosis.
- c) Active transport.
- d) Facilitated diffusion.
Answer: c.
Question 20. The cell wall of algae is made up of?
- a) Cellulose, galactans, mannans, and calcium carbonate.
- b) Cellulose, hemicellulose, pectins, and proteins.
- c) Chitin, galactans, and lipids.
- d) Peptidoglycan and teichoic acid.
Answer: a.
Question 21. Which layer primarily holds or glues the different neighbouring plant cells together?
- a) Primary cell wall.
- b) Secondary cell wall.
- c) Middle lamella.
- d) Plasmodesmata.
Answer: c.
Question 22. The middle lamella is mainly composed of?
- a) Magnesium pectate.
- b) Calcium pectate.
- c) Sodium chloride.
- d) Cellulose microfibrils.
Answer: b.
Question 23. Which of the following is NOT considered a part of the endomembrane system?
- a) Endoplasmic reticulum.
- b) Golgi complex.
- c) Mitochondria.
- d) Lysosomes.
Answer: c.
Question 24. Rough Endoplasmic Reticulum (RER) is primarily involved in?
- a) Lipid synthesis.
- b) Protein synthesis and secretion.
- c) Glycogen metabolism.
- d) Steroid hormone synthesis.
Answer: b.
Question 25. In animal cells, lipid-like steroidal hormones are synthesised in the?
- a) Rough Endoplasmic Reticulum.
- b) Smooth Endoplasmic Reticulum.
- c) Golgi apparatus.
- d) Mitochondria.
Answer: b.
Question 26. Camillo Golgi first observed densely stained reticular structures near the nucleus in the year?
- a) 1838.
- b) 1855.
- c) 1898.
- d) 1953.
Answer: c.
Question 27. The convex face of the Golgi cisternae is also known as the?
- a) Maturing face.
- b) Trans face.
- c) Cis or forming face.
- d) Secretory face.
Answer: c.
Question 28. Which cell organelle is the major site for the formation of glycoproteins and glycolipids?
- a) Endoplasmic reticulum.
- b) Lysosome.
- c) Golgi apparatus.
- d) Peroxisome.
Answer: c.
Question 29. Lysosomes are rich in hydrolytic enzymes optimally active at?
- a) Basic pH.
- b) Neutral pH.
- c) Acidic pH.
- d) Variable pH depending on the cell cycle.
Answer: c.
Question 30. In plant cells, the vacuole can occupy up to what percentage of the volume of the cell?
- a) 50 percent.
- b) 70 percent.
- c) 90 percent.
- d) 99 percent.
Answer: c.
Question 31. The membrane bounding the vacuole in a plant cell is called the?
- a) Plasma membrane.
- b) Tonoplast.
- c) Mesosome.
- d) Elaioplast.
Answer: b.
Question 32. Which organelle in Amoeba is important for osmoregulation and excretion?
- a) Food vacuole.
- b) Contractile vacuole.
- c) Lysosome.
- d) Golgi body.
Answer: b.
Question 33. Which of the following organelles is typically sausage-shaped or cylindrical having a diameter of 0.2-1.0 µm?
- a) Chloroplast.
- b) Mitochondrion.
- c) Centriole.
- d) Lysosome.
Answer: b.
Question 34. The inner membrane of mitochondria forms a number of infoldings called?
- a) Cisternae.
- b) Cristae.
- c) Thylakoids.
- d) Grana.
Answer: b.
Question 35. Which of the following organelles divide by fission and contain a single circular DNA molecule?
- a) Golgi apparatus.
- b) Endoplasmic reticulum.
- c) Mitochondria.
- d) Peroxisomes.
Answer: c.
Question 36. Plastids that store carbohydrates (starch), like in potatoes, are known as?
- a) Elaioplasts.
- b) Aleuroplasts.
- c) Amyloplasts.
- d) Chromoplasts.
Answer: c.
Question 37. Fat and oils are stored in which type of plastid?
- a) Amyloplast.
- b) Elaioplast.
- c) Aleuroplast.
- d) Chloroplast.
Answer: b.
Question 38. The flat membranous tubules connecting the thylakoids of the different grana in a chloroplast are called?
- a) Cristae.
- b) Stroma lamellae.
- c) Cisternae.
- d) Plasmodesmata.
Answer: b.
Question 39. The ribosomes of chloroplasts are?
- a) Larger than cytoplasmic ribosomes (80S).
- b) Smaller than cytoplasmic ribosomes (70S).
- c) Exactly the same as cytoplasmic ribosomes (80S).
- d) Devoid of RNA.
Answer: b.
Question 40. Ribosomes were first observed under the electron microscope as dense particles by George Palade in the year?
- a) 1931.
- b) 1953.
- c) 1972.
- d) 1981.
Answer: b.
Question 41. In the 80S ribosome, what does 'S' stand for?
- a) Synthesis unit.
- b) Svedberg's Unit.
- c) Structural unit.
- d) Standard coefficient.
Answer: b.
Question 42. Svedberg's unit is primarily an indirect measure of?
- a) Density and size.
- b) Volume and mass.
- c) Mass and surface area.
- d) Charge and density.
Answer: a.
Question 43. An elaborate network of filamentous proteinaceous structures present in the cytoplasm is collectively referred to as the?
- a) Endomembrane system.
- b) Cytoskeleton.
- c) Plasmodesmata.
- d) Glycocalyx.
Answer: b.
Question 44. The core of a cilium or flagellum is called the?
- a) Axoneme.
- b) Basal body.
- c) Centrosome.
- d) Radial spoke.
Answer: a.
Question 45. The arrangement of axonemal microtubules in eukaryotic cilia and flagella is referred to as?
- a) 9 + 0 array.
- b) 9 + 2 array.
- c) 8 + 2 array.
- d) 6 + 3 array.
Answer: b.
Question 46. Both the cilium and flagellum emerge from a centriole-like structure called the?
- a) Kinetochore.
- b) Centromere.
- c) Basal body.
- d) Axoneme.
Answer: c.
Question 47. Centrosome is an organelle usually containing two cylindrical structures called?
- a) Cilia.
- b) Centrioles.
- c) Chromosomes.
- d) Cristae.
Answer: b.
Question 48. The peripheral fibrils of a centriole are arranged as?
- a) Doublets.
- b) Triplets.
- c) Singlets.
- d) Tetrads.
Answer: b.
Question 49. The central part of the proximal region of the centriole is proteinaceous and called the?
- a) Axoneme.
- b) Hub.
- c) Radial spoke.
- d) Microtubule organizing center.
Answer: b.
Question 50. Material of the nucleus stained by the basic dyes was given the name chromatin by?
- a) Robert Brown.
- b) Walther Flemming.
- c) Anton Von Leeuwenhoek.
- d) Rudolf Virchow.
Answer: b.
Question 51. The space between the two parallel membranes of the nuclear envelope is called the?
- a) Perinuclear space.
- b) Intermembrane space.
- c) Nucleoplasm.
- d) Cytosol.
Answer: a.
Question 52. The outer membrane of the nuclear envelope usually remains continuous with the?
- a) Golgi apparatus.
- b) Endoplasmic reticulum.
- c) Mitochondria.
- d) Plasma membrane.
Answer: b.
Question 53. Movement of RNA and protein molecules takes place in both directions between the nucleus and the cytoplasm through the?
- a) Nuclear matrix.
- b) Nucleolus.
- c) Nuclear pores.
- d) Plasmodesmata.
Answer: c.
Question 54. Which of the following cells typically lacks a nucleus at maturity?
- a) Companion cells of vascular plants.
- b) Sieve tube cells of vascular plants.
- c) White blood cells.
- d) Muscle cells.
Answer: b.
Question 55. The site for active ribosomal RNA (rRNA) synthesis is the?
- a) Nucleoplasm.
- b) Rough Endoplasmic Reticulum.
- c) Nucleolus.
- d) Centromere.
Answer: c.
Question 56. During different stages of cell division, cells show structured objects in place of the nucleus called?
- a) Chromatin.
- b) Chromosomes.
- c) Nucleoli.
- d) Centrosomes.
Answer: b.
Question 57. The primary constriction present on every chromosome is known as the?
- a) Telomere.
- b) Centromere.
- c) Kinetochore.
- d) Secondary constriction.
Answer: b.
Question 58. Disc-shaped structures situated on the sides of the centromere are called?
- a) Centrioles.
- b) Chromatids.
- c) Kinetochores.
- d) Satellites.
Answer: c.
Question 59. A chromosome with a centromere situated close to its end forming one extremely short and one very long arm is called?
- a) Metacentric.
- b) Sub-metacentric.
- c) Acrocentric.
- d) Telocentric.
Answer: c.
Question 60. The chromosome in which the centromere is exactly at the middle forming two equal arms is called?
- a) Metacentric.
- b) Sub-metacentric.
- c) Acrocentric.
- d) Telocentric.
Answer: a.
Question 61. A telocentric chromosome has its centromere located?
- a) In the middle.
- b) Slightly away from the middle.
- c) Close to its end.
- d) At the terminal end.
Answer: d.
Question 62. The non-staining secondary constrictions on chromosomes at a constant location give the appearance of a small fragment called the?
- a) Satellite.
- b) Kinetochore.
- c) Centrosome.
- d) Nucleolus organizer region.
Answer: a.
Question 63. Microbodies are membrane-bound minute vesicles that contain?
- a) DNA and RNA.
- b) Various enzymes.
- c) Hormones.
- d) Excretory waste.
Answer: b.
Question 64. According to the NCERT syllabus, a single human cell has approximately how much long thread of DNA distributed among its 46 chromosomes?
- a) 1 meter.
- b) 2 meters.
- c) 3 meters.
- d) 4 meters.
Answer: b.
Question 65. Which of the following represents the correct sequence of layers in a typical bacterial cell envelope from outside to inside?
- a) Cell wall, Glycocalyx, Plasma membrane.
- b) Plasma membrane, Cell wall, Glycocalyx.
- c) Glycocalyx, Cell wall, Plasma membrane.
- d) Glycocalyx, Plasma membrane, Cell wall.
Answer: c.
Question 66. The bacterial flagellar filament is mainly composed of the protein?
- a) Tubulin.
- b) Flagellin.
- c) Actin.
- d) Myosin.
Answer: b.
Question 67. The phenomenon of active transport across the cell membrane requires?
- a) ATP energy.
- b) Only a concentration gradient.
- c) Transport vesicles exclusively.
- d) Aquaporins.
Answer: a.
Question 68. The fluid mosaic model of the cell membrane was proposed by Singer and Nicolson in which year?
- a) 1935.
- b) 1953.
- c) 1972.
- d) 1981.
Answer: c.
Question 69. Statement 1: Ribosomes are non-membrane bound organelles found only in eukaryotic cells. Statement 2: Centrioles are non-membrane bound organelles that help in cell division. Which of the following is correct?
- a) Both Statement 1 and Statement 2 are correct.
- b) Statement 1 is incorrect but Statement 2 is correct.
- c) Statement 1 is correct but Statement 2 is incorrect.
- d) Both Statement 1 and Statement 2 are incorrect.
Answer: b.
Question 70. Mycoplasmas are distinct from other bacteria because they?
- a) Lack a cell wall.
- b) Have a very thick cell wall.
- c) Cannot survive without oxygen.
- d) Do not possess genetic material.
Answer: a.
Question 71. The largest isolated single cell is the egg of an?
- a) Emu.
- b) Ostrich.
- c) Elephant.
- d) Eagle.
Answer: b.
Question 72. Which cell organelle is frequently referred to as the 'suicidal bag' of the cell?
- a) Golgi apparatus.
- b) Lysosome.
- c) Vacuole.
- d) Peroxisome.
Answer: b.
Question 73. Which of the following combinations correctly describes the composition of a typical plant cell wall?
- a) Peptidoglycan, teichoic acid, lipids.
- b) Cellulose, hemicellulose, pectins, proteins.
- c) Chitin, galactans, mannans.
- d) Phospholipids, sterols, sphingolipids.
Answer: b.
Question 74. The Golgi apparatus remains in close association with the endoplasmic reticulum because?
- a) They share the same lumen.
- b) Materials synthesised by the ER migrate to the Golgi for packaging.
- c) Golgi provides energy to the ER.
- d) Both lack membranes.
Answer: b.
Question 75. The tonoplast facilitates the transport of a number of ions and other materials against concentration gradients into the?
- a) Cytoplasm.
- b) Vacuole.
- c) Mitochondria.
- d) Nucleus.
Answer: b.
Question 76. In chloroplasts, the stroma contains enzymes required for the synthesis of?
- a) Carbohydrates and proteins.
- b) Lipids and steroids.
- c) Only proteins.
- d) Only ATP.
Answer: a.
Question 77. Which organelle possesses single circular DNA, a few RNA molecules, and 70S ribosomes?
- a) Nucleus.
- b) Lysosome.
- c) Mitochondrion.
- d) Golgi complex.
Answer: c.
Question 78. In a 9+2 arrangement of axonemal microtubules, how many radial spokes are present?
- a) 2.
- b) 9.
- c) 18.
- d) 11.
Answer: b.
Question 79. What connects the central tubules in the axoneme of cilia and flagella?
- a) Radial spoke.
- b) Central sheath.
- c) Linkers.
- d) Bridges.
Answer: d.
Question 80. Identify the incorrect statement regarding the nucleolus.
- a) It is a spherical structure found in the nucleoplasm.
- b) It is a membrane-bound structure.
- c) It is a site for active ribosomal RNA synthesis.
- d) Larger and more numerous nucleoli are present in cells actively carrying out protein synthesis.
Answer: b.
Question 81. Chromatin contains DNA and some basic proteins known as?
- a) Albumins.
- b) Globulins.
- c) Histones.
- d) Non-histones exclusively.
Answer: c.
Question 82. Which of the following provides mechanical support, motility, and maintenance of the shape of the cell?
- a) Glycocalyx.
- b) Cytoskeleton.
- c) Endoplasmic reticulum.
- d) Golgi apparatus.
Answer: b.
Question 83. The term "Prokaryote" implies that the organism?
- a) Has a primitive true nucleus.
- b) Lacks a true, membrane-bound nucleus.
- c) Consists of multiple nuclei.
- d) Contains a well-developed endomembrane system.
Answer: b.
Question 84. Polysomes function to translate mRNA into?
- a) Lipids.
- b) Proteins.
- c) Carbohydrates.
- d) Nucleic acids.
Answer: b.
Question 85. The polar heads of lipids in a typical cell membrane are oriented towards?
- a) The inner part of the membrane.
- b) The outer environments, facing the aqueous environments.
- c) The hydrophobic tails exclusively.
- d) The integral proteins only.
Answer: b.
Question 86. Which type of membrane proteins can be easily extracted from the cell membrane?
- a) Integral proteins.
- b) Transmembrane proteins.
- c) Peripheral proteins.
- d) Carrier proteins.
Answer: c.
Question 87. Osmosis is the movement of water across a semi-permeable membrane. It is a form of?
- a) Active transport.
- b) Facilitated diffusion.
- c) Passive transport.
- d) Exocytosis.
Answer: c.
Question 88. Secondary cell wall is formed?
- a) On the outer side of the primary wall.
- b) On the inner side of the cell, towards the membrane.
- c) By replacing the middle lamella.
- d) Only in the dividing meristematic cells.
Answer: b.
Question 89. Which enzyme-rich organelle is responsible for digesting worn-out cellular organelles?
- a) Peroxisome.
- b) Lysosome.
- c) Smooth Endoplasmic Reticulum.
- d) Vacuole.
Answer: b.
Question 90. Amoeba engulfs its food particles by a process which involves the formation of a?
- a) Contractile vacuole.
- b) Food vacuole.
- c) Mesosome.
- d) Dictyosome.
Answer: b.
Question 91. The ATP synthase enzyme in mitochondria is located primarily on the?
- a) Outer membrane.
- b) Inner membrane (cristae).
- c) Matrix.
- d) Intermembrane space.
Answer: b.
Question 92. The space limited by the inner membrane of the chloroplast is known as the?
- a) Matrix.
- b) Stroma.
- c) Lumen.
- d) Grana.
Answer: b.
Question 93. Chlorophyll pigments are primarily located within the?
- a) Stroma.
- b) Inner chloroplast membrane.
- c) Thylakoids.
- d) Intermembrane space.
Answer: c.
Question 94. The eukaryotic 80S ribosome comprises which two subunits?
- a) 50S and 30S.
- b) 60S and 40S.
- c) 70S and 10S.
- d) 40S and 30S.
Answer: b.
Question 95. The basal body of cilia and flagella arises from which of the following cellular components?
- a) Centrioles.
- b) Kinetochores.
- c) Centromeres.
- d) Microfilaments.
Answer: a.
Question 96. Which scientist originally discovered the nucleus in 1831?
- a) Robert Hooke.
- b) Robert Brown.
- c) Walther Flemming.
- d) Rudolf Virchow.
Answer: b.
Question 97. Assertion: The endoplasmic reticulum divides the intracellular space into luminal and extraluminal compartments. Reason: The ER is a network of tiny tubular structures scattered in the cytoplasm.
- a) Both Assertion and Reason are true, and Reason is the correct explanation of Assertion.
- b) Both Assertion and Reason are true, but Reason is not the correct explanation of Assertion.
- c) Assertion is true, but Reason is false.
- d) Both Assertion and Reason are false.
Answer: b.
Question 98. Match the shape of chromosomes with their centromere position: (A) Metacentric (i) Terminal, (B) Sub-metacentric (ii) Middle, (C) Acrocentric (iii) Slightly away from middle, (D) Telocentric (iv) Close to end.
- a) A-ii, B-iii, C-iv, D-i.
- b) A-i, B-ii, C-iii, D-iv.
- c) A-ii, B-iv, C-iii, D-i.
- d) A-iv, B-iii, C-ii, D-i.
Answer: a.
Question 99. Which pair of organelles does not contain DNA?
- a) Mitochondria and Chloroplasts.
- b) Chloroplasts and Nucleus.
- c) Lysosomes and Vacuoles.
- d) Nucleus and Mitochondria.
Answer: c.
Question 100. During the analysis of a cell, you observe an extensive network of rough endoplasmic reticulum. This indicates that the cell is highly active in?
- a) Lipid metabolism.
- b) Carbohydrate synthesis.
- c) Protein synthesis and secretion.
- d) Osmoregulation.
Answer: c.


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